Q. This has been the scariest week of my life. I suddenly developed very high blood pressure (195/118) and had to go to the emergency department.
I'm a student and had bought a ton of black licorice, the really good imported kind. I had been eating it while I studied and didn't realize my blood pressure had begun to rise.
I was put on hypertension medications: first, a beta blocker that did nothing; then an ACE inhibitor (ditto) and a water pill. The diuretic brought my pressure down after several days. Eventually it got my pressure down to 87/63, which is too low. Now my pressure is back to normal without medicine.
I could not understand what was happening. It wasn't until afterward that my brother told me he thought it was glycyrrhizin toxicity from licorice. I could not believe it could be so harmful. Today, my blood pressure is fine without medication: 107/70. I'm never eating licorice again.
A. Too much licorice can raise blood pressure and lower potassium levels (Clinical Chemistry, December 2009). Your brother is right that glycyrrhizin in natural licorice is the culprit. Candy flavored with anise rather than real licorice is safe. The imported variety that you were consuming is more likely to contain glycyrrhizin.
Q. My husband was just released from the hospital as a result of taking naproxen for tendinitis. He used it exactly as prescribed, and it still caused trouble.
He had severe gastrointestinal bleeding, so bad that he needed a blood transfusion with three units of blood. He was in ICU for four days. The doctor and nurses said that people who take high doses of this pain reliever often end up with gastrointestinal bleeding. What other options are there for pain and inflammation?
A. Naproxen and other NSAIDs, such as Celebrex, ibuprofen, diclofenac, meloxicam and nabumetone, are frequently prescribed for inflammatory conditions like tendinitis, bursitis and arthritis. Long-term use of such drugs poses a risk of life-threatening bleeding like your husband experienced. They also can raise blood pressure and increase the risk of heart attacks, heart failure and strokes (Rheumatology International online, Dec. 22, 2011).
Acetaminophen (Tylenol) is less likely to cause digestive upset or bleeding, but it may raise blood pressure (Circulation, Nov. 2, 2010) and increase the risk of asthma (Pediatrics, Dec. 2011). High doses can be hard on the liver.
Such complications may explain why home remedies are so popular. Fish oil, tart cherries, gin-soaked raisins, grape juice and apple-cider vinegar, vitamin D and pineapple all have their enthusiasts. Our Guide to Alternatives for Arthritis provides details on how to use such approaches.
Anyone who would like a copy, please send $3 in check or money order with a long (No. 10), stamped (65 cents), self-addressed envelope to:
Graedons' People's Pharmacy
No. AA-2, P.O. Box 52027
Durham, N.C. 27717-2027
It also can be downloaded for $2 from our website: PeoplesPharmacy.com.
Topical NSAID gels and lotions may be one way to ease joint pain or tendinitis without as much risk of side effects.


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