Medical Research Roundup

Medical Research Roundup

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Following are some of the medical research grants awarded to area scientists:

St. Louis College of Pharmacy:

The scientist • Tom Burris, alumni chair in pharmaceutical education and vice president for research

The grant • $740,000 from Mallinckrodt Pharmaceuticals

The study • To develop drugs targeting muscle function; specifically, the creation of therapeutics to treat Duchenne muscular dystrophy and muscle loss caused by aging, known as sarcopenia.

St. Louis University School of Medicine:

The scientist • Andy Nguyen, assistant professor of internal medicine-geriatrics and pharmacology and physiology

The grant • $1.9 million from the National Institutes for Health and $219,943 from the Bluefield Project to Cure FTD

The study • To test an antisense oligonucleotide-based therapeutic approach for progranulin-deficient frontotemporal dementia.

The scientist • Jeffrey Scherrer, professor of family and community medicine, and Timothy Wiemken, associate professor in the SLU Center for Health Outcomes Research

The grant • $290,896 from the Benter Foundation

The study • To study common adult vaccinations and incident dementia

The scientist • Amelia Pinto, assistant professor of molecular microbiology and immunology

The grant • $302,870 from the U.S. Department of Defense

The study • To investigate the use of anti-inflammatory viral proteins to treat sepsis

The scientist • Dr. Guangyong Peng, professor of internal medicine-infectious diseases

The grant • $1.68 million from the National Cancer Institute

The study • The research will dissect molecular mechanisms responsible for effective T cell senescence and develop effective strategies to prevent tumor-specific T cell senescence for anti-tumor immunity.

The scientist • Dr. Guangyong Peng, professor of internal medicine-infectious diseases

The grant • $1.73 million from the National Cancer Institute

The study • To identify the metabolic profiles of breast cancer tumor-infiltrating DCs and Treg cells and to develop enhanced tumor immunotherapy in breast cancer.

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