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Pluton Biosciences, Evolugate Enter License Agreement to Advance Bacteria Strains for Commercial Biopesticide Development

Pluton Biosciences, Evolugate Enter License Agreement to Advance Bacteria Strains for Commercial Biopesticide Development


Pluton Biosciences, LLC is pleased to announce that it has entered into an exclusive license agreement with biotechnology company Evolugate of Gainesville, FL to optimize its mosquito biopesticide discovery for commercial use in the vector control industry.

Headquartered in St. Louis, MO, Pluton Biosciences discovers new beneficial microbes in the soil for use in sustainable, natural products. Pluton used its high-throughput microbial discovery platform called Micromining® to discover 10 new strains of bacteria with insecticidal properties. Some of these strains are especially effective against mosquitoes. Mosquitoes carry several deadly infectious diseases, including Malaria, Zika, Dengue, West Nile and Yellow Fever. The sheer number of diseases that mosquitoes can spread, combined with their widespread distribution, make mosquitoes one of the deadliest animals on earth.

“Even now with COVID-19, control of mosquito populations remains a priority for human health,” said Pluton CEO Charlie Walch. “Through our development partnership with Evolugate, we can develop a new multi-strain natural larvicide to treat standing water sources where mosquitoes breed – killing the larvae before they have a chance to grow to adulthood. Pluton’s goal is to help pesticide makers replace synthetic chemicals with safe, effective natural products. We see this larvicide as the first of many microbial-based products we will discover for the market through Micromining.”

Under the exclusive agreement, Evolugate will identify the most effective combination of Pluton’s parent strains, then use its proprietary Evolugator™ evolution technology to apply the maximum selective pressure needed to push these organisms to commercial efficacy. The commercial-ready bacteria can then be licensed to companies for the development of natural insecticides.

“We think that Pluton’s Micromining platform and its ability to find previously indecipherable, advantageous organisms, coupled with our evolutionary technology will enable us to make Pluton’s microbial discovery commercially viable,” said Evolugate CEO Eudes de Crecy. “Our company will bridge the gap between Pluton’s discovery and it ultimately becoming a commercialized product to help protect the health of so many around the world.”

About Pluton Biosciences

Headquartered in St. Louis, Missouri, Pluton Biosciences researches and mines beneficial microbes in the soil for use in sustainable bioproducts across a variety of industries, including pesticide, agriculture, pharmaceutical, and bioremediation. Pluton’s Micromining platform targets new microbial solutions quickly and inexpensively, speeding the introduction of novel natural products through the research and development pipeline to market. For more information about Pluton Biosciences, visit

About Evolugate

Evolugate, LLC, a privately-owned biotechnology company, is the leading evolution biotechnology company that focuses on the development and improvement of microorganisms for diverse industrial purposes. Evolugate’s technology offers the ability to improve existing bio-processes as well as to create new ones through the utilization of a reliable and proprietary continuous culture technology. Using rapid evolution and natural selection, Evolugate is able to improve microorganisms for use in the biopesticides, probiotics, agronomy, pharmaceutical, and bioremediation industries while its sister company, BioTork LLC, operates in the fields of biofuels, feed and food ingredients, nutraceuticals, cosmetics, and other fine chemicals. The company is located in Gainesville, Florida. For more information, visit

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